Advancing Imaging and Image Analysis

In Medicines Discovery

Join us at the ELRIG Pharmaceutical Flow Cytometry & Imaging 2021 meeting from November 30th – December 1st

Complex cell models provide a more reliable way to study the effects of medicines on disease. As cell models continue to become more complex, consideration of the entire workflow from image acquisition through to processing and analysis is vital.​ Extract all the information from your sample.

Come and speak to us and arivis at stand B7 to learn more about the very latest possibilities in the imaging world.

  • Learn about the newest developments and how to tackle new experiments in your research
  • How to extract all the information from your cell model
  • Learn how to get deeper insights from your image data with arivis

Case studies: From Image to Results

Extracting all the information from your sample requires key workflow optimization. This includes the most suitable imaging platform and image analysis workflows. In this new series "From Image to Results", explore various examples explaining how to reach results from your demanding samples and acquired images in an efficient way. For each case study, we highlight different samples, imaging systems, and research questions.

Vesicle Trafficking

Case Study Overview

Sample

Cos7 cells transiently transfected with mEmerald-Rab5a and Golgi7-tdTomato.

Task

Track both types of vesicles, volume & distances over time, colocalization​.

Results

Graphic visualization of tracks and cells in a movie and resulting data as time line along track, scatter plots.

System

ZEISS Lattice Lightsheet 7

Software

arivis Vision4D

Organoid Analysis

Case Study Overview

Sample

Intestinal organoids

Task

Study the role of Wnt signaling in organoid formation

Results

Analysis of an organoid experiment

System

ZEISS Celldiscoverer 7

Software

arivis Vision4D®

High Content Imaging for Genotoxicity

Case Study Overview

Sample

Clear-cell renal carcinoma cell line SLR22

Task

DNA-damage analysis

Results

Cell-cycle specific DNA-damage elucidates drug mechanism

System

ZEISS Axio Observer

Software

arivis Vision4D

arivis Vision4D

arivis Vision4D is a modular software for working with multi-channel 2D, 3D and 4D images of almost unlimited size, highly scalable and independent of local system resources. Many modern microscope systems such as high-speed confocal, light sheet / SPIM, super-resolution, electron microscopy or X-ray instruments can produce huge amounts of imaging data. arivis Vision4D handles such datasets without constraints and in relatively short time.

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Get in touch to discuss how ZEISS and arivis can advance your imaging and image analysis in medicines discovery.