Microscience Microscopy Congress (MMC) 2025

We are proud to present the UK debut of our new LSM with Lightfield 4D. In this workshop we will focus on a number of new innovations, the first being the new Lightfield 4D with its ability to capture volumes in a single snap and collect volumes at speeds of 80 volumes per second. Continuing the theme of speed, we’ll also explore the new jDCV for Airyscan MPLX. Finally, we will have a discussion with our new AI assistant, Copilot, a powerful LLM based assistant who can aid you in all manner of microscopy challenges.

We are please to offer demo opportunities on our Lattice SIM 3 system. This fast optical sectioning system can revolutionise your imaging through offering fast, high resolution imaging across a flexible range of magnifications. Allowing you to image large areas of your sample quickly, collect fast optically sectioned z stacks or collect fast dynamics from your sample. This flexible system speed up existing workflows or enable ones that would have been too time consuming. We will have a collection of samples to explore or bring your own to explore on the Lattices SIM3!

Targeted high resolution 3D data acquisition of vitrified biological samples based on immuno-fluorescence labeling is an ongoing challenge. In this tutorial we demonstrate the combination of cryo light microscopy (LM) with cryo FIB-SEM to generate 3D datasets from ROIs that have been identified using a confocal laser scanning microscope. We show the cryo equipment that was designed to facilitate the safe transfer of cryo samples between the different microscopes under liquid nitrogen conditions. Correlating the LM and FIB-SEM coordinate systems allows navigation to the ROIs followed by FIB-SEM tomography or preparation of TEM lamella for cryo electron tomography. A few experimental results will illustrate the utility of the workflow.

Experience seamless imaging of biological samples in 3D across extensive areas with our latest In-Chamber Ultramicrotome for Serial Block-Face SEM, the ZEISS Volutome. This comprehensive end-to-end solution integrates advanced hardware and software, featuring a dedicated Volume BSD Detector and integrated Focal Charge Compensation for high-quality imaging of all resin-embedded biological samples.

The intuitive workflow streamlines sample installation, automated cutting, image acquisition, preprocessing, and 3D visualization.
Join our remote session to explore the ZEISS Volutome, witness live image acquisitions, and see final ultrastructural results, including 3D visualizations of segmented SBF data in ZEISS arivis pro. Additionally, we will provide a brief demonstration on collecting Array Tomography data using ZEISS ATLAS AT.

Acquiring high resolution images of structure generally requires the use of destructive methods to physically section the sample. In this remote session, we will explore how X-ray microscopy can offers new insights through the ability to collect high resolution 3D data without the need for sectioning, while working on a range of samples from delicate soft tissues and embryos to plant tissues. We will discuss innovations like resolution at a distance(RaaD) that allow capture of large regions without loss of resolution and the advanced reconstruction toolbox(ART), a powerful software suite with tools to improve speed of acquisition and reconstruction quality.

Discover how the GeminiSEM 460 can reveal the intricate microstructures of energy materials such as battery cathodes and separator membranes. This demo will highlight how SEM helps understand performance, degradation, and design of next-generation energy storage systems.

Discover how ZEISS VersaXRM’s FAST Mode accelerates acquisition of 3D datasets. This demo will show rapid 3D scans using the flat panel extension for efficient, high-quality imaging of complex materials.

Experience how ZEISS Crossbeam, powered by ZEN Core, automates TEM lamella preparation. This demo will show precision milling, site-specific targeting, and streamlined workflows for high-throughput sample prep.

See how ZEN Core powers end-to-end SEM workflows—from image acquisition to advanced analysis. This demo will highlight how a unified platform enhances productivity, reproducibility, and data integrity.