Image captured with ZEISS ELYRA. Lattice SIM: Comparison of widefield and Lattice SIM images of a Cos-7 cell undergoing mitosis stained for actin (Phalloidin Alexa Fluor 568, magenta), microtubules (anti-beta-tubulin Alexa Fluor 488, yellow) and nucleus (Hoechst, blue). Images are maximum intensity projections of 30 planes of a total depth of 3.19 µm. Objective: Plan-Apochromat 63×/1.4 Oil
Conference

Microscience Microscopy Congress (MMC) 2023

Emerging Trends in Advanced Microscopy

Manchester | United Kingdom
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  • ZEISS Elyra 7 and Workstation
  • ZEISS Celldiscoverer 7 and Workstation
  • ZEISS GeminiSEM 560
  • ZEISS Sigma 500
  • ZEISS Crossbeam 350
  • ZEISS Lattice Lightsheet 7 and Workstation
  • ZEISS Elyra 7 and Workstation

    ZEISS Elyra 7

  • ZEISS Celldiscoverer 7

  • ZEISS GeminiSEM 560

    ZEISS GeminiSEM 560

  • ZEISS Sigma 500

    ZEISS Sigma 500

  • ZEISS Crossbeam 350

    ZEISS Crossbeam 350

  • ZEISS Lattice Lightsheet 7 and Workstation

    ZEISS Lattice Lightsheet 7

Overview

Microscience Microscopy Congress (MMC) 2023 is back in person and will take place from 4th - 6th July 2023 at the Manchester Convention Centre, UK. Bringing you the latest in microscopy the event will feature six parallel conference sessions covering a varied range of microscopy, cytometry and imaging topics, workshops and a world-class exhibition.

We are proud to be the sustainability partner for this year’s MMC, and we have designed our stand with this in mind. Therefore, to reduce the environmental impact of physically moving microscopes to the event, the majority of our product demonstrations will be virtual. Visit us on stand 111 to virtually experience a selection of our most innovative systems. (Featured right) We will also host a special event with talks from noteworthy women in STEM or you can attend one of our workshops to find out more about sustainability and careers at ZEISS.

People at a ZEISS exhibition stand

Meet Our Specialists

You can find us at stand 111, near the poster section in the main exhibition space. Our specialists will be on hand to answer any questions you have about our microscopes and to discuss the latest innovation across various microscopy applications. There will be many exciting activities at our stand all throughout the congress, including a Women In STEM event, virtual and live microscope system demos and a binoculars prizedraw!

We look forward to seeing you there!

Demo Summary and Booking

  • Live Cell Super Resolution Imaging - ZEISS Elyra 7 With SIM² (Virtual Demo)

    ZEISS Elyra 7 pushes the boundaries of what is possible in live cell super resolution imaging. With our innovative SIM² processing capabilities, it is now possible to double the conventional SIM resolution to reach 60 nm xy resolution. You also benefit from our powerful lattice illumination which facilitates faster, more gentle imaging and reaches acquisition speeds of 255 fps. Enabling researchers to access new levels of speed and resolution when imaging live samples.

    During this virtual demo you will learn and see:

    • Collection of live cell SIM2 data
    • How the Elyra 7 reaches 255 fps in live cells
    • How Apotome SIM2 can speed up your optical section
  • Smart Microscopy - ZEISS Celldiscoverer 7 With LSM900 (Virtual Demo)

    ZEISS Celldiscoverer 7 with LSM900 is your smart and automated live cell imaging system. Combining smart features, like sample carrier material recognition to ensure the best image quality, with intelligent acquisition features like Guided Acquisition. This intuitive system helps you efficiently narrow down your areas of interest, by allowing the system to find these for you and collect high resolution images at the click of a button. The system also makes use of our latest AI driven tools to offer new powerful ways to solve your image analysis conundrums.

    During this virtual demo you will learn and see:

    • How the system adapts to the sample to maximize image quality automatically
    • How the system can be used to find rare events automatically and return for high resolution imaging
    • How the outputs can be intuitively displayed in image analysis pipelines

      

  • Explore the Power of Serial Block-face Imaging - ZEISS Volutome (NEW Virtual Demo)

    A serial block-face solution for SEM (SBF-SEM) will be demonstrated by a live webcast from the ZEISS headquarters in Germany. With an ultramicrotome located inside the SEM chamber, a resin-embedded sample can be automatically imaged and cut until the desired – or entire – stack is acquired in the Z direction of the sample.

    Serial block-face SEM (SBF-SEM) is a technology of choice when the user is interested in easy sample preparation, a highly automated imaging process, and a higher Z-resolution than what is found with array tomography. With ZEISS Focal Charge Compensation, the technique is more robust and can also be used for charge prone samples which was only possible at the expense of image quality before.  To learn more about this technology and volume EM please visit: www.zeiss.com/volume-em

    In this remote demo you will learn:

    • How to cut resin-embedded biological samples with an in-chamber ultramicrotome
    • How to acquire images with SBF-SEM and Sense BSD – easy, fast and at low KV
    • The high image quality of non-conductive biological sample by using Focal Charge Compensation
    • How to acquire single tile images
    • How to acquire mosaic images
  • Live Stand Demo of the ZEISS Lattice Lightsheet 7

    ZEISS Lattice lightsheet 7 brings unprecedented speed and gentleness to live cell imaging at subcellular resolutions. The Lattice lightsheet 7 redefines how long you can image live samples, while also enabling up to 3 volumes per second imaging. Seamlessly capture fast dynamics in 3D or observe samples for considerably longer at high resolution – forget your current limitations, tell us the experiments you dream of running!

    During this live demo you will learn and see:

    • Fast volumetric imaging of live cells
    • Gentleness of the Lattice lightsheet
    • How easy the system is to operate
  • Optimised Imaging at Low Voltages - ZEISS GeminiSEM 560 (Virtual Demo)

    Non-conductive materials with nano-scale details is becoming more and more important for SEM analyses today. Imaging at low voltages reveal surface-sensitive information at high resolution while avoiding charging of the sample. ZEISS GeminiSEM 560 raises the bar for surface sensitive, high resolution imaging and facilitates imaging below 1kV easily thanks to the Gemini 3 column.

    During this virtual demo you will learn and see:

    • How the FE-SEM combines the latest hardware and software technology in the analysis and characterisation of various materials at low voltages.
    • A range of samples reaching from battery separator membranes to magnetic materials and composite materials.
    • Samples investigated both for topographical contrast and for material contrast, if applicable.
    • Smart Autopilot function
  • In Situ Tensile Stage With EBSD - ZEISS Sigma 500 (Virtual Demo)

    Automated tensile experiments with EBSD analysis

    During this virtual demo you will learn and see:

    • Up to 800°C and 5kN tensile tests
    • Automated site tracking
    • How to automatically acquire EBSD datasets at regular intervals
  • Accessing Buried Features by Correlative X-ray Microscopy to LaserFIB Workflows - ZEISS Xradia Versa and Crossbeam 350 Laser (Virtual Demo)

    For some time it has been possible to correlate X-ray microscopy volume scans with surface features visible in the FIB-SEM. X-ray data can be used to virtually localise sub-surface features in 3D to the precisely targeted FIB sites. However, users have been limited to near surface volumes.

    Femto-second laser ablation now allows researchers to access much larger volumes, so deeply buried structures can be accessed directly in a FIB-SEM. This Sample-In-Volume analysis is a powerful workflow for targeting regions of interest buried far below the sample surface.

    During this virtual demo you will learn and see:

    • The set-up and operation of an Xradia Versa
    • How an XRM volume is used to correlatively target ROIs in the FIB
    • High speed, high volume milling with the fs-Laser
    • Post-laser mill imaging of exposed sample ROI

Demonstrations

Our online demo bookings are now closed. There is still some limited availability, visit us at stand 111 for further information.

Women in STEM

We are proud to support Women in STEM. For the first time at MMC, we are hosting a dedicated event to showcase some of the women who are making a difference in the field of microscopy. Our aim is not only to celebrate the remarkable contributions by our speakers but to also highlight the varied and exciting career paths available in the scientific industry. Join us at stand 111 for a collection of short talks delivered by female leaders in their respective fields.  This event is open to all, registration is not required.

Career Spotlight Talks

We are proud to host a series of short and informative talks, presented by female innovators in the field of microscopy. Our speakers will share about their personal career journey in the scientific industry and also which microscopy topics that they are passionate about. This is your opportunity to hear from industry leaders and to interact with your peers. Join in the conversation!

  • How Did I End Up Here, and the Women Who Inspired Me Along the Way

  • Up-close - Life as a Microscopist

  • Seeing Into Cells

  • Correlative Imaging of Plant-soil Interactions

Speaker

Dr. Jemima Burden

Electron Microscopy Leader, University College London

Talk: How did I end up here, and the women who inspired me along the way
Join this session to hear about the women who have inspired Jemima on her incredible career path, and the topics that spark her curiosity.

  

Speaker Bio: Jemima is Head of Electron Microscopy (EM) at the Laboratory for Molecular Cell Biology at University College London. She received her BSc from University of Bath and her PhD from Imperial College London, where her fascination for microscopy began. Her main interests are Correlative Light and Electron Microscopy and using volume EM to investigate cell biological processes - from viruses to whole organisms.

Speaker

Dr. Kerry Thompson

Imaging Scientist Research Fellow and Assistant Professor in Anatomy, University of Galway

Talk: Up-Close - Life as a Microscopist
Kerry will discuss her path to becoming an imaging scientist and the work she does with the Royal Microscopical Society and Global Bioimaging.

  

Speaker Bio: Kerry Thompson is a Chan Zuckerberg Initiative funded Imaging Scientist in the Anatomy Imaging and Microscopy Facility (AIM) and a Lecturer in Anatomy, School of Medicine in the University of Galway. Her current work focuses on the establishment of doctoral training programmes in Microscopy and Imaging, technology development to assist multidisciplinary teams and career progression pathways for Imaging Scientists and Core Facility Staff. She is the Honorary Secretary for Education for the Royal Microscopical Society and Chairs the Outreach and Education Committee, and Co-Chairs the Career Development for Imaging Core Facility Staff Working Group for Global Bioimaging.

Speaker

Professor Michelle Peckham

Professor of Cell Biology, University of Leeds

Talk: Seeing Into Cells
Microscopy is a key tool in our research. In this talk I will briefly summarise how I started using microscopy, and how I developed and exploited various forms of microscopy, from super-resolution to CryoEM, as well as developing novel tools for microscopy, to enable me to explore my interests in the cytoskeleton and gain a better understanding of its role in cells.

  

Speaker Bio: After a degree in Biology (University of York) and a PhD in muscle energetics (UCL). I worked at KCL (Biophysics) on muscle birefringence, UCSF on fluorescence polarisation then the University of York on insect flight muscle kinetics. I started my own lab as a Royal Society University Research Fellowship at KCL, then moved to the University of Leeds in 1997, becoming Professor in 2010. Over this time, I developed a strong interest in imaging and confocal microscopy alongside my interests in the cytoskeleton, developing super-resolution approaches at Leeds about 10 years ago, and more recently structural biology approaches including Cryo-EM. I was president of the Royal Microscopical Society from 2016-2019 and am currently its Executive Honorary Secretary.

Speaker

Dr. Ria Mitchell

Applications Development Engineer, Carl Zeiss Ltd

Talk: Correlative Imaging of Plant-soil Interactions
The evolution of the first plant-based terrestrial ecosystems ~500 million years ago had a profound effect on the development of soils, the architecture of sedimentary and river systems, and shifts in global biogeochemical cycles (e.g., carbon). Ria and team studied the macro-to-nano scale interactions occurring in modern analogous plants (the bryophytes) and their substrates to elucidate some of the processes occurring, such as bio-weathering of mineral grains, and stabilization of sediment surfaces. They applied a correlative, multi-dimensional (2D-to-3D) and multi-modal workflow across XRM/X-ray micro CT, FIB-SEM, LM, and SEM, together with SEM-EDS, to understand these processes.

  

Speaker Bio: Ria is an Earth Scientist who has previously worked in both geoscience and materials science university departments as a researcher studying a range of subjects from multi-scale and multi-dimensional bioweathering in soils to bioinspiration for human-made materials. Ria has a background in correlative imaging predominantly using X-ray CT/XRM and FIB-SEM, but also SEM and LM.

Speaker

Dr. Jemima Burden

Electron Microscopy Leader, University College London

Talk: How did I end up here, and the women who inspired me along the way
Join this session to hear about the women who have inspired Jemima on her incredible career path, and the topics that spark her curiosity.

  

Speaker Bio: Jemima is Head of Electron Microscopy (EM) at the Laboratory for Molecular Cell Biology at University College London. She received her BSc from University of Bath and her PhD from Imperial College London, where her fascination for microscopy began. Her main interests are Correlative Light and Electron Microscopy and using volume EM to investigate cell biological processes - from viruses to whole organisms.

Speaker

Dr. Kerry Thompson

Imaging Scientist Research Fellow and Assistant Professor in Anatomy, University of Galway

Talk: Up-Close - Life as a Microscopist
Kerry will discuss her path to becoming an imaging scientist and the work she does with the Royal Microscopical Society and Global Bioimaging.

  

Speaker Bio: Kerry Thompson is a Chan Zuckerberg Initiative funded Imaging Scientist in the Anatomy Imaging and Microscopy Facility (AIM) and a Lecturer in Anatomy, School of Medicine in the University of Galway. Her current work focuses on the establishment of doctoral training programmes in Microscopy and Imaging, technology development to assist multidisciplinary teams and career progression pathways for Imaging Scientists and Core Facility Staff. She is the Honorary Secretary for Education for the Royal Microscopical Society and Chairs the Outreach and Education Committee, and Co-Chairs the Career Development for Imaging Core Facility Staff Working Group for Global Bioimaging.

Speaker

Professor Michelle Peckham

Professor of Cell Biology, University of Leeds

Talk: Seeing Into Cells
Microscopy is a key tool in our research. In this talk I will briefly summarise how I started using microscopy, and how I developed and exploited various forms of microscopy, from super-resolution to CryoEM, as well as developing novel tools for microscopy, to enable me to explore my interests in the cytoskeleton and gain a better understanding of its role in cells.

  

Speaker Bio: After a degree in Biology (University of York) and a PhD in muscle energetics (UCL). I worked at KCL (Biophysics) on muscle birefringence, UCSF on fluorescence polarisation then the University of York on insect flight muscle kinetics. I started my own lab as a Royal Society University Research Fellowship at KCL, then moved to the University of Leeds in 1997, becoming Professor in 2010. Over this time, I developed a strong interest in imaging and confocal microscopy alongside my interests in the cytoskeleton, developing super-resolution approaches at Leeds about 10 years ago, and more recently structural biology approaches including Cryo-EM. I was president of the Royal Microscopical Society from 2016-2019 and am currently its Executive Honorary Secretary.

Speaker

Dr. Ria Mitchell

Applications Development Engineer, Carl Zeiss Ltd

Talk: Correlative Imaging of Plant-soil Interactions
The evolution of the first plant-based terrestrial ecosystems ~500 million years ago had a profound effect on the development of soils, the architecture of sedimentary and river systems, and shifts in global biogeochemical cycles (e.g., carbon). Ria and team studied the macro-to-nano scale interactions occurring in modern analogous plants (the bryophytes) and their substrates to elucidate some of the processes occurring, such as bio-weathering of mineral grains, and stabilization of sediment surfaces. They applied a correlative, multi-dimensional (2D-to-3D) and multi-modal workflow across XRM/X-ray micro CT, FIB-SEM, LM, and SEM, together with SEM-EDS, to understand these processes.

  

Speaker Bio: Ria is an Earth Scientist who has previously worked in both geoscience and materials science university departments as a researcher studying a range of subjects from multi-scale and multi-dimensional bioweathering in soils to bioinspiration for human-made materials. Ria has a background in correlative imaging predominantly using X-ray CT/XRM and FIB-SEM, but also SEM and LM.

Women in STEM Profiles

In addition to our spotlight talks, we want to also celebrate a selection of the incredible Women in STEM here at Zeiss. Visit us at stand 111 to meet some of these women and to hear about how their career path led to their current roles at Zeiss.

Profile

Dr. Delisa Garcia

Business Development Software Solutions, Carl Zeiss Ltd

Amongst the many careers I could have pursued, I chose science… Specifically, chemistry because I wanted to understand the chemical processes underlying life. I have two masters, one in Chemistry at the university of Valencia and one in Biomolecular Sciences at Imperial College. My interest in chemistry led me into synthesising porphyrins, this led me into working with lasers and doing a PhD in Biophysics.

  

I did my PhD and Post Doc at Imperial College where I discovered the world of microscopy and image processing. I worked with different microscopy techniques, its applications to biological samples and image analysis processes. After my Post Doc I left the university to work in the corporate world which has provided me with a new range of opportunities that combine science and business which I really love. I worked for many years as a Scientific Liaison and account manager and nowadays I work as a business developer for software at ZEISS.

  

A career in science might not be exactly what you envision at the beginning, but science opens infinite doors to diverse professional development. You just have to be curious enough to "knock"!

  

  

Profile

Soné Hendriks

Head of Sales and Service, Microscopy Division South Africa, Carl Zeiss Ltd

I obtained my MSc Genetics whilst working at the Core Imaging Facility at the University of Pretoria. For my research I used ZEISS confocal and fluorescence microscopes to study the intracellular trafficking of viral proteins of African Horse Sickness Virus.


I joined ZEISS as an account manager in 2011 focusing on Routine and Education microscopy. In 2014, I got promoted as local sales and applications support specialist for all automated microscopy solutions with application to brightfield, widefield and confocal microscopy throughout Africa.

  

I took up the role as Head of the Microscopy division in 2019 and I am privileged to lead a driven, success hungry team of sales specialists, service engineers and distribution partners in 21 African countries . Our passion is to educate, develop and support African scientists with enabling microscopy technologies to drive science that contributes to growth on the African continent.

Profile

Dr. Rosy Manser

Solution Manager for X-ray Microscopy in Life Science, Carl Zeiss Ltd

Rosy became fascinated by microscopy during her PhD when she used confocal microscopes extensively to explore preimplantation embryo development. In 2008 Rosy joined ZEISS UK as an imaging specialist focusing on the laser-based 3D instruments including confocal, super resolution and lightsheet microscopy.

 

Rosy took responsibility for the X-ray microscopy portfolio in the UK in 2015 and was immediately struck by the vast range of specimens that can be explored, particularly in biological research. Having progressed through a number of global roles, Rosy now works in the life science division as a solution manager where she supports the global ZEISS team in developing applications, sharing expertise and defining future requirements for the ZEISS portfolio of X-ray instruments.

Profile

Dr. Alexandra F. Elli

Manager Business Sector Life Sciences BioEM/CorrMic, Carl Zeiss Ltd

Alexandra Elli is the Manager Business Sector Life Sciences for Electron Microscopy and Correlative Microscopy in Life Sciences. As a biochemist, she made the bold choice to do her PhD in physics and used microscopic techniques to study the energy transfer of individual photosystem I complexes.

  

Before joining ZEISS in 2011, Alexandra was running an academic core imaging facility. During this time, her main research interest was on the study of kidney cancer. At ZEISS she started as a product manager for correlative microscopy before she became the manager for BioEM and CorrMic. While she was working at ZEISS, she also pursued an MBA and successfully completed it.

ZEISS Presentations at MMC

Some of our experts are contributing to the MMC 2023 agenda through different presentations and talks. We are pleased to share microscopy advancements and cutting edge technology in collaboration with research partners. Below is a list of the conference tracks where you can see our speakers.

Commercial Workshops

Wednesday July 5th, 2023

Workshop Stream 2 - 11:15 BST

Sustainability at ZEISS Research Microscopy Solutions - Ideas and projects for a resource-efficient and innovative future
Mr. Corey Alguire
Carl Zeiss Ltd, Cambourne, United Kingdom

Learn More

Wednesday July 5th 2023

Workshop Stream 3 - 13:00 BST

Career Development @ ZEISS
Ms. Helen Garrett
Carl Zeiss Ltd, Cambourne, United Kingdom

Learn More
  

Poster Presentations

Tuesday July 4th, 2023

Poster Session One - 16:30 - 18:30 BST

Novel automated approaches for studying extended in situ mechanical and high temperature transformations of materials and alloys in electron and X-ray microscopy
Mr Andy Holwell1, Dr Fang Zhou2
1 Carl Zeiss Microscopy Ltd, Cambridge, United Kingdom. 2 Carl Zeiss Microscopy GmbH, Oberkochen, Germany

Learn More

Tuesday July 4th, 2023

Poster Session One - 16:30 - 18:30 BST

Novel techniques in X-ray nanotomography and high resolution FESEM imaging: linking structure and catalytic properties of heterogeneous and automotive catalysts in two and three dimensions
Mr Andy Holwell1, Dr Maadhav Kothari1, Dr Markus Boese2, Dr Dogan Ozkaya3, Dr Aakash Varambhia3
1 Carl Zeiss Microscopy Ltd, Cambridge, United Kingdom. 2 Carl Zeiss Microscopy GmbH, Oberkochen, Germany. 3 Johnson Matthey plc, Sonning Common, United Kingdom

Learn More

Conference Sessions

Tuesday July 4th, 2023

Microscopy to Modelling - 15:30 BST

Investigation of stress corrosion cracking in CMSX-4 turbine blade alloys using Deep Learning assisted X-ray microscopy and using 3D images for finite element modelling
Mr Andy Holwell1, Dr Hrishikesh Bale2, Mr Mustafa Elsherkisi3, Dr Maadhav Kothari1
1 Carl Zeiss Microscopy Ltd, Cambridge, United Kingdom. 2 Carl Zeiss X-ray Microscopy LLC, Dublin, CA, USA. 3 Cranfield University, Cranfield, United Kingdom

Learn More

Thursday July 5th, 2023

Correlative and Multimodal X-ray Microscopy -  12:05 BST

Electron Microscopy Sample Preparation with Femto-second Laser Ablation
Dr. Andrew Elliott
ZEISS, Cambourne, United Kingdom

Learn More

Previous User Group Meetings

Still not sure what to expect? In June 2023, we hosted an Array Tomography User Group Meeting, this is what some attendees had to say about the event.

  • Array Tomography User Group Meeting Experience

One thing that I think I would take away from this event is the sense of community and the sense of shared learning and shared experience. It's really important for us microscopists as a community to meet in person to be able to share ideas organically.

Kirsty MacLellan-Gibson

Senior Electron Microscopist, Babraham Institute - Cambridge

I think my research benefits greatly from user meetings like this. When you come together with a group of specialists in the field and you hear about different ways, that people are approaching the same problems and tips and tricks that they have. It's really invigorating.

Errin Johnson

Electron Microscopy Facility Manager, University of Oxford