The future is

minimally invasive

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30 years of refractive surgery evolution

Corneal refractive laser surgery has been widely used to correct vision impairment for over 30 years. Three generations of techniques, in particular, have shaped the field of laser vision correction.


Watch the video to experience these major milestones:

Surface ablation

  • Subepithelial ablation
  • Excimer laser treatment
  • Extended visual recovery time
  • Patient discomfort


  • Stromal ablation
  • Excimer laser treatment or combined with femtosecond laser
  • Quick visual recovery
  • Some risk of flap complications

Minimally invasive, flapless surgery

  • Intrastromal lenticule extraction
  • Femtosecond laser treatment
  • Gentle treatment
  • No flap complications
    (e.g. less incidence of dry eye)
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1st Generation


With PRK, the visual correction is made directly to the surface of the cornea. Patients experience a difference the same day. However, visual recovery generally takes longer than with other procedures and is frequently accompanied by some discomfort.

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2nd Generation


LASIK is a widely used laser vision correction procedure, with which excellent results are achieved. Visual recovery is quick and patients generally experience no complications following surgery. A higher incidence of dry eye has been noted in some studies as compared with SMILE.

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3rd Generation


SMILE is a minimally invasive surgical procedure. Because it requires no flap, the outer corneal layer remains largely intact. As a result, there is less risk of post-surgical complications such as infections or epithelial ingrowth. The overall treatment is gentle and visual recovery is fast.

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Show treatment animations
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Minimally invasive, flapless surgery

Small incision lenticule extraction, or SMILE, combines the advantages of PRK and LASIK. With this minimally invasive, flapless procedure, a lenticule is created inside the intact cornea and extracted through a small incision. Because there is no flap, there are no flap-related complications. It thus enables more biomechanical preservation and stability along with less incidence of dry eye. SMILE is redefining refractive surgery as we know it.

Find out why refractive specialists are full of praise about the qualities of SMILE.

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“I operated on my own 18-year-old daughter with SMILE, so what more can I say?”

“Patients want quality of vision and a high level of safety. That´s why we choose SMILE. Small incision – great patient satisfaction.” 


“We love doing minimally invasive surgery because it's faster, safer, more gentle on the patient and it delivers really good results.“

“Convincing, long-term follow-up results with SMILE mean that this is a technique that's here to stay.“

Dr. Petri Oksman, Finnland
Medilaser Oy, Tampere
ESCRS 2014 London

Dr. Joaquin Fernández, Spain
Qvision, Almeria
ESCRS 2014 London

Dr. David Donate, France
Centre Laser Vision Roosevelt, Lyon
ESCRS 2014 London 

Prof. Walter Sekundo, Germany
Phillips University Marburg
DOG 2014 Leipzig 

Experience SMILE in clinical usage

Prof. Dan Reinstein, United Kingdom, London Vision Clinic

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Find out more about the only SMILE solution available today!

Become part of the 3rd generation of laser vision correction.


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Experience SMILE firsthand – at the ZEISS live surgery
at ESCRS Barcelona, 2015.


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Get in touch with us

For additional information materials on SMILE and the three generations of laser vision correction, simply contact us.

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